To determine whether dPSA co-localization with nucleolin was unique to SK-MEL-28 cells or common to cancer cells, we performed similar confocal fluorescence microscopy experiments labeling dPSA with SEAM 2 and nucleolin with anti-nucleolin mAb MS-3 on sets of seven pancreatic, five gastric, four ovarian primary and metastatic cell lines (Additional file 3, Supplementary Figs. S8-S10, respectively). The gene discussed is NUCLEOLIN; the disease is cancer.