CCR7 and CCL19 played an important role in organizing thymic architecture and function, lymph-node homing of naive and regulatory T cell, as well as homeostasis and inflammation-induced lymph-node-bound migration of dendritic cells, which indicated that CCR7 and CCL19 involved in the homeostasis, immune surveillance, and tumor formation [34]. This evidence concerns the gene CCR7 and neoplasm.