As expected, the Transwell assay showed no significant difference in the numbers of invaded cells treated with the miR-1180-3p mimics or inhibitors after knocking down ST3GAL4 (Fig. 6G, H) (Additional file 6: Figure S5), supporting our hypothesis that miR-1180-3p regulates the malignant phenotype of melanoma by targeting ST3GAL4. Here, ST3GAL4 is linked to melanoma.