Further, in viral hepatitis B and C related cirrhosis, AST/ALT ratio is shown to have a prognostic capability and lower ratios are found to be related to the survival of patients [31].We evaluated the AST/ALT ratio in our patients with dengue associated acute severe hepatitis, but difference between day 1 and day 4 ratios did not reach a statistical significance. The gene discussed is GPT; the disease is hepatitis A virus infection.