In summary, in this time course study that models early events after virus infection, we identified in total 661 unique CpG-dependent TF genes that show significant differential expression in at least one condition compared to another (|FC| > 2, p < 0.05, pDC at steady state, or after CpG activation at 2 h, 6 h, 12 h). The gene discussed is TF; the disease is viral infectious disease.