Through comparing the prevalence of gene mutations in these two groups, the mutation rates of NRAS, MET, and NFE2L2 were higher in the recurrence subgroup than in the recurrence‐free subgroup when considering preoperative and postoperative ctDNA mutations, indicating that those gene mutations might be predictors for HCC early intrahepatic recurrence (Fig. 1, Table S1). The gene discussed is NRAS; the disease is hepatocellular carcinoma.