We identified genes for which ASEs were observed in both the Afro-Caribbean cohort and the Jurkat cells expressing Tax or HBZ, including cancer genes EIF4A2, IKBKB, LZTR1, STAT6 (for Tax); CARS, MDM2, IKZF1 (for HBZ); and EWSR1, MUTYH, and PTPRC (for both Tax and HBZ) (Fig 6C and 6D). The gene discussed is IKZF1; the disease is cancer.