IL27 and autoimmune disease: Numerous previous GWAS studies of autoimmune diseases have identified rs3024505 as significantly associated with multiple autoimmune diseases including T1D, inflammatory bowel disease, Behçet’s disease, and others.[31–33] Furthermore, a number of the genetic variants identified in this study were nearby Sharp et al. variants and regulated the same gene targets including in the IL27 and UBASH3A loci (S5 Fig).[15] In addition, 24/40 Sharp et al. gene targets were identified using our pipeline with GM12878 input data.