For instance, in colon and lung cancers, cancer‐associated fibroblasts (CAFs) secrete Netrin‐1 and take part in a two‐way signaling process with cancer cells, which involve the secretion of stemness‐promoting cytokines such as interleukin‐6 (IL‐6), resulting in an increased stemness phenotype of cancer cells (Sung et al, 2019). This evidence concerns the gene IL6 and cancer.