RAN translation is supported by many repeat expansions including CGG repeats associated with FXTAS and GGGGCC repeats associated with ALS/FTD (Ash et al, 2013; Mori et al, 2013; Todd et al, 2013; Bañez‐Coronel et al, 2015; Ishiguro et al, 2017; Zu et al, 2017; Soragni et al, 2018). This evidence concerns the gene RAN and amyotrophic lateral sclerosis.