Considering a pleiotropic role of TGF‐β signaling on tumorigenesis, such as cancer cell proliferation, metastasis, chemoresistance, even on angiogenesis25, 26, 27 and based on a fact that VEGF induces the EMT and cancer stemness through cross talk with TGF‐β,28, 29 we further investigated synergism between TGF‐β receptor inhibitor, TEW‐7197, and ramucirumab. Here, VEGFA is linked to cancer.