TGFB1 and cancer: Considering a pleiotropic role of TGF‐β signaling on tumorigenesis, such as cancer cell proliferation, metastasis, chemoresistance, even on angiogenesis25, 26, 27 and based on a fact that VEGF induces the EMT and cancer stemness through cross talk with TGF‐β,28, 29 we further investigated synergism between TGF‐β receptor inhibitor, TEW‐7197, and ramucirumab.