SCP2 and pachyonychia congenita: AS reflected by dual‐luciferase reporter gene assay, FOXP3 overexpression inhibited SCP2 luciferase activity; FOXP3 silencing increased luciferase activity of SCP2 in PC cells relative to sh‐NC (Figure 3I), suggesting that FOXP3 could specifically inhibit SCP2 expression in PC cells.