A previous study has shown that HCC lesions with gadoxetic acid uptake have overexpression of OATP1B3 compared to lesions with no uptake (Narita et al. 2009), and RTE had a perfect correlation (correlation coefficient of 0.91) with OATP1B3 levels on immunohistochemical staining. The gene discussed is SLCO1B3; the disease is hepatocellular carcinoma.