HIV infection is an independent risk factor for VTE, which puts thenumber of HIV-positive patients in this study (41%) in perspective.There is a higher incidence of VTE in HIV-positive patients withlower CD4 counts, which is related to an increasing hypercoagulablestate as occurs with progressive immune suppression.[9–11] Most HIV-infected patients diagnosed with PE in this study had a CD4 count<200 cells/μL, which is known to cause a higher risk of thrombosisthan in patients with higher CD4 counts.[9–11]. The gene discussed is CD4; the disease is HIV infectious disease.