Brain sections showed that the number of iNOS+/IBA1+ cells around the hematoma was significantly increased at 3 days after ICH to approximately 44.87 ± 3.21, while administration of PIH effectively decreased the number to 25.09 ± 3.05 (Figures 5(a) and 5(b)), thus indicating that PIH inhibited microglial M1 polarization. Here, AIF1 is linked to hematoma.