PPARA and Encephalopathy: Bezafibrate, a pan-PPAR agonist, can significantly increase the levels of CD36, ACOX1, CPTI, CPT II, and uncoupling protein-2/3 (UCP-2/3), improve mitochondrial ΔΨm, restore intracellular ATP level, and further improve IAV-associated encephalopathy [27].