For the outcome of hypertension, we observed that the elevated urinary uromodulin level could increase the risk of hypertension in dataset “ukb-b-14057” (Oodds ratio (OR) = 1.036, 95% CI, 1.029–1.043, P = 3.07E−26) and “ukb-b-14177” (OR = 1.036, 95% CI, 1.030–1.044, P = 3.29E−26) (Table 1). This evidence concerns the gene UMOD and hypertensive disorder.