The other two studies found that HDAC2 significantly under-expressed in anaplastic oligoastrocytoma (n = 6) with a fold change of 4.40 (p = 5.95E-04), and in GBM (n = 22) with a fold change of 3.68 (p = 2.70E-10). The gene discussed is HDAC2; the disease is anaplastic oligoastrocytoma.