CD74 and glioblastoma: Then we applied CD74 as the potential biomarker to facilitate the diagnosis of GBM, results showed that CD74 had moderate predictive accuracy with the area under the curve (AUC) of 0.808, 0.681, 0.676, and 0.622 in TCGA, CGGA, CGGA301, and GSE108474 datasets, respectively (p < 0.05) (Figure 8D).