The most well-known signaling pathways for resveratrol include the induction of autophagy by an increased activation and expression of sirtuin1 (SIRT1), the inhibition of protein kinase B/mammalian target of rapamycin (Akt/mTOR), and the activation of p38-mitogen-activated protein kinase (MAPK) as observed in cases of non-small-cell lung cancer (NSCLC) (Wang et al., 2018). This evidence concerns the gene SIRT1 and non-small cell lung carcinoma.