TF and cancer: Nonetheless, some studies have successfully demonstrated the toxicity of selective cancer cells in their proposed nanoparticle formulations, studying relevant normal and cancer cells: peptide lipid CDO and sucrose laurate L126 liposomes in MCR-5 and MCR-7 cells (breast cancer) (Zhao et al., 2019); sericin nanoparticles in CRL-2522 and Caco-2 cells (colorectal cancer) (Suktham et al., 2018); and Tf-modified PEG-PLA nanoparticles in C6, U87, and rat astrocyte cells (glioma) (Jhaveri et al., 2018).