IL17A and chronic kidney disease: Th17/IL-17 axis seems to increase the risk of CKD itself, as seen in a genetic study with 650 elderly, where single nucleotide polymorphism (SNP) of IL17RA (rs4819554 AA homozygotes) was significantly more frequent among individuals with eGFR < 60 ml/min/1.73 m2; and was associated to the risk of developing ESRD (40).