AQP3 and hepatocellular carcinoma: CircHIPK3 acts as a miR-124 sponge to regulate its downstream target gene aquaporin 3 (AQP3), promoting the proliferation and metastasis of HCC cells, while silencing circHIPK3 inhibits the proliferation and migration of HCC cells in vitro and delaying the growth rate of subcutaneous xenografts in vivo (47).