CircZKSCAN1 blocks the binding of fragile X mental retardation protein (FMRP) to cell division cycle and apoptosis regulator 1 (CCAR1) mRNA by competitively binding to FMRP, and subsequently inhibits the transcriptional activity of the Wnt/β-catenin signaling pathway, thereby inhibiting the malignant biology behaviors of HCC cells by regulating the stemness of HCC cells (71). The gene discussed is FMR1; the disease is hepatocellular carcinoma.