AKT1 and neoplasm: Resveratrol presents anticancer effects by inhibiting GLUT1 via the protein kinase B (AKT)/mTOR-dependent signaling pathway and targeting “classical” tumor-promoting pathways, such as PI3K/AKT, signal transducer and activator of transcription (STAT)3/5, and mitogen-activated protein kinase (MAPK), which enhance glycolysis via the upregulation of glycolytic enzymes and glucose transporters (37).