A collaboration between GLUT1 inhibitors and chemotherapeutic drugs significantly facilitates apoptosis and chemosensitivity in breast cancer, oral squamous cell carcinoma, and laryngeal cancer (29, 32, 35), and mannose-conjugated platinum complexes are effective in cancer targeting mediated by GLUT1 (36). Here, SLC2A1 is linked to oral cavity squamous cell carcinoma.