Notably, the expression of DCLK 3 was reported to be significantly elevated in colon cancer tissues, compared to the healthy controls The study also revealed that DCLK3 was significantly co-expressed with common EMT markers (such as CALD1 and FN1), strongly suggesting that DCLK3 is a potential oncogene that is associated with EMT and tumor progression (32). This evidence concerns the gene CALD1 and malignant colon neoplasm.