To validate in vivo the light‐induced cell killing mediated by LiPOP1, we generated a xenograft mouse model of solid tumors by injecting HeLa‐LiPOP1 cells or HeLa‐mCh‐CRY2 as the negative control into the flanks of immunodeficiency mice (Figure 2). The gene discussed is CRY2; the disease is immunodeficiency disease.