Moreover, whereas the concentrations of nesfatin-1 in the circulation in women diagnosed with GDM according to Coustan and Carpenter (C&C) and WHO criteria were lower than controls, it was determined higher in pregnant women with GDM diagnosed in accordance with the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria compared to the control group [29]. Here, NUCB2 is linked to diabetes mellitus.