For XRCC4, its higher level was involved in a worse OS in grade I (HR=3.92 (1.42-10.85), P=0.0049), also a worse PFS and OS in grade III ovarian carcinoma women (PFS: HR=1.38 (1.16-1.65), P=0.0004; OS: HR=1.56 (1.32-1.85), P=0.0000). The gene discussed is XRCC4; the disease is ovarian carcinoma.