On the contrary, NPC patients with positive expression of PD-1 (P=0.031, Figure 4B), p-S6 (P =0.044, Figure 4C) or co-expression of PD-1 and PD-L1 (P=0.042, Figure 4D) had shorter survival time than others by univariate analysis. Here, CD274 is linked to nasopharyngeal carcinoma.