For instance, the TCM formula Guchang Zhixie Wan (GCZXW) exerts a protective effect on IBD through the STAT3/NF-kB/IL-6 pathway, and the active ingredients of the Banxia Xiexin decoction (BXXXD) primarily act on IL-4, IL-10, IL-1β, and TNF-α [4, 5]. This evidence concerns the gene TNF and inflammatory bowel disease.