For example, transmembrane serine protease 2 (TMPRSS2) inhibitors (e.g., camostat) were reported as potential treatments for COVID-19 since host cell factors such as TMPRSS2 and ACE2 are critical for successful virus replication during SARS-CoV-2 infection (Hoffmann et al., 2020a,b; Wang et al., 2021). The gene discussed is ACE2; the disease is COVID-19.