The deletion of 2.7 Mbp at chromosome 18q22.1, which contains three genes, CDH19, DSEL, and TXNDC10/TMX3 encoding cadherin 19, DSEL/DSE2, and thioredoxin domain-containing protein10/thioredoxin related transmembrane protein 3, respectively, causes diaphragmatic hernia (Zayed et al., 2010). This evidence concerns the gene CDH19 and diaphragmatic hernia.