SLC7A11 and cancer: Xu et al. (2020) found that IFN- γ secreted in tumor tissues by infiltrating lymphocytes can help downregulate expression of SLC7A11, thereby promoting tumor cell ferroptosis and decreasing tumor volume. Efimova et al. (2020) observed that dendritic cells can be induced to mature and active by phagocytosis of early ferroptotic cancer cells.