Studies have confirmed that overexpression of PCLAF in adrenal cortical tumors, nasopharyngeal carcinoma, and hepatocellular carcinoma may promote the growth and invasion of cancer cells (Jain et al., 2011; Abdelgawad et al., 2016; Ma et al., 2020). The gene discussed is PCLAF; the disease is nasopharyngeal carcinoma.