The CD4/CD8 ratio (T vs. CSD + T and T vs. CSD + T + CSD, both p < 0.05; Figure 4E) and proportion of immunosuppressive CD11b+ myeloid cells infiltrating into the tumor microenvironment were markedly increased in CSD mice (T vs. CSD + T + CSD and T + CSD vs. CSD + T + CSD, both p < 0.05; Figure 4F). This evidence concerns the gene ITGAM and neoplasm.