SOX10 and neoplasm: At the phylum level, significant changes were found between the tumor and paired adjacent normal mucosae [false discovery rate (FDR) q ≤ 0.1], with enrichment of Fusobacteria and Synergistetes, and decrease of Cyanobacteria, Actinobacteria, Gemmatimonadetes, Acidobacteria, TM7, Chlorobi, Verrucomicrobia, Chloroflexi, OD1, Armatimonadetes, OP3, [Thermi], Nitrospirae, WPS-2, Elusimicrobia, BRC1, GOUTA4, Deferribacteres, Fibrobacteres, GN02, Planctomycetes, SR1, WS4, and AC1 in the tumor mucosae (Figures 5A, B and Additional File 6).