Moreover, the expression level of chemokine CXCL11 and CCL5 in the adjacent normal tissues was significantly lower in advanced stage CRC (stages IV, n = 11; p = 0.027 and p = 0.0001; Figure 1G) than those in early stages (stages I, II, and III, n = 18). The gene discussed is CCL5; the disease is colorectal carcinoma.