We divided the 95 CSU patients into eight pairs of subgroups according to eight aspects: elevated/normal tIgE, positive/negative anti-TPO IgG, positive/negative anti-TG IgG, with/without angioedema, refractory/non-refractory, UASday > 4/UASday ≤ 4, disease duration > 6 months/disease duration ≤ 6 months, and recurrent/non-recurrent. Here, TPO is linked to angioedema.