TNF and Jeune syndrome: The DMGs were enriched in the pathways related to autoimmune diseases including IBD, ATD, and TID, as well as important immune-related pathways including antigen processing and presentation, Th17 cell differentiation, Th1 and Th2 cell differentiation, PI3K-Akt signaling pathway, TNF signaling pathway, and AMPK signaling pathway, which play important roles in autoimmune diseases.