It is very likely that NK cells are not the sole mediators of anti-tumor immunity in vivo and our analyses revealed that enrichment of the CD8+ memory T cell phenotype in LGG tumors was also associated with improved prognosis when LGG tumors were stratified for high or low tumor expression of PDGFD in both TCGA and CGGA patient cohorts. The gene discussed is PDGFD; the disease is neoplasm.