The anticancer effect of Ang 1-7 through MASR has been proven by different studies where Ang 1-7 was able to inhibit fibrosis, reduce tumour weight and volume (40, 51), restore mesenchymal epithelial transition, as well as impede angiogenesis and metastasis induced by Ang II through inhibition of VEGF and MMP-9 expression (42). This evidence concerns the gene VEGFA and neoplasm.