In inflammatory neuropathies, subcutaneous injection of BDNF had been tried on GBS patients to improve recovery (27); however, the results did not support its therapeutic use because of the small sample size, nonsignificant effects on improving disability after 4 weeks [mean difference, 0.75; 95% confidence interval, −1.14 to 2.64; very low certainty of the evidence (77)], and early termination of the trial. Here, BDNF is linked to Guillain-Barre syndrome.