Unlike earlier results of positive correlation between Foxm1 and HCC, our transcriptomic profile demonstrated that fold change of Foxm1 was rather reduced in Phb1+/− compared with WT (Phb1+/− vs. WT, log2 FC = −1.6) (Supplementary Material 3) and then increased in Phb1−/− compared with Phb1+/− (Phb1−/− vs. Phb1+/−, log2 FC = 4.6) (data not shown). This evidence concerns the gene PHB1 and hepatocellular carcinoma.