IL1F10 and arthritic joint disease: Moreover, after injection of adeno-associated virus IL-38 (AAV IL-38) into the joints of CIA and serum transfer induced arthritis (STIA) mice, the clinical inflammatory score was decreased significantly, accompanied by decreased macrophage infiltration and decreased expression levels of IL-17, IL-22, IL-23, and TNF-α (Boutet et al., 2017).