STAT5B and cancer: The tumor suppressor gene CIS and the oncogene c-Myc are the target genes of STAT5, α-Br-TMC down-regulated c-Myc and up-regulated CIS in Ba/F3-1*6 cells, therefore, α-Br-TMC is expected to be used in the treatment and intervention of STAT5 related malignant tumors in the future (Pinz et al., 2014).