The induce apoptosis and inhibit migration activity of herbs at the interface of food and medicine was investigated in gastric carcinoma, and a food composed of six plants, Coix seed, Lentinula edodes, Asparagus officinalis L., H. cordata, Taraxacum mongolicum Hand.-Mazz., and Grifola frondose, was used to treat gastric carcinoma in nude mice inoculated with SGC-7901 cells; supplementing 43.22, 86.44, and 172.88 g/kg food for 30 days, the serum levels of MMP-2 and MMP-9 decreased, while TNF-α significantly increased. This evidence concerns the gene MMP2 and gastric carcinoma.