MTOR and hereditary disease: This is a genetic disorder associated with the mTOR signaling pathway that results in epileptic activity in most individuals afflicted with the disease and is characterized by significant alterations in the relationships between glia and neurons (reviewed in Curatolo et al., 2002, 2015; Chu-Shore et al., 2010; Sofroniew and Vinters, 2010; Zimmer et al., 2020).