The enriched GO terms of BP, CC, and MF category referred to nucleus, extracellular exosome, cytoplasm, focal adhesion, and metal ion binding, ATP binding, etc. KEGG analysis showed that genes were significantly enriched in several crucial pathophysiological processes in stroke, such as ubiquitin-mediated proteolysis and signaling pathways in cancer, glioma, chronic myeloid leukemia, and chemokine signaling, etc. This evidence concerns the gene CXCR1 and stroke disorder.