Autoimmune/inflammatory disorders comprised Tolosa–Hunt syndrome (n = 13), ocular myasthenia gravis (n = 5; presence of acetylcholine-receptor antibodies), multiple sclerosis (n = 4), Miller-Fisher syndrome (n = 3), giant-cell arteritis (n = 3) and less common diseases such as Morbus Wegener (granulomatosis with polyangiitis; high titer of cANCA) and systemic lupus erythematosus. Here, PRTN3 is linked to multiple sclerosis.