High expressions of these genes (TNFSF14, TNFSF4, TNFRSF25, TNFRSF6B, TNFRSF1A, RELT, and LTBR) were associated with a poor prognosis, and low expressions of these genes (TNFRSF19, TNFRSF10A, HHLA2, EDA, CD274, and TNFSF15) were associated with a poor prognosis in ccRCC. The gene discussed is TNFSF4; the disease is nonpapillary renal cell carcinoma.