Recently, casein kinase 1-alpha (CK1α) was discovered as a novel promising autophagy regulator in the lung, breast, multiple myeloma, and colon cancer cells (Cai et al. 2018; Carrino et al. 2019; Cheong et al. 2015; Szyniarowski et al. 2011). The gene discussed is CSNK1A1; the disease is colonic neoplasm.