RAG1 and RUNX1 transcripts levels are positively and significantly correlated exclusively in ETV6-RUNX1 BCP-ALL compared to other childhood BCP-ALL (Fig. 1A, Supplementary Fig. S1A), suggesting either a common regulator for RAG1 and RUNX1 (or ETV6-RUNX1) expression, or a dependency between them. The gene discussed is ETV6; the disease is acute lymphoblastic leukemia.