IFNG and neoplasm: As IFN-γ is a key cytokine produced by the immune cells during the anti-tumor immune response, we examined the expression of the IFN-γ-related genes28 and found that, except for patient FAL-SA (patient 71, Table 1), another two patients in group A had extremely low baseline expression of many IFN-γ-related and other immune genes (Fig. 4).